PROTEUS

Special notes & news about ENH122

* NEW (From Dr. Sly, 20 Feb, 2015): Re: Case Fatality Rate calculation (CFR): The examples I gave in the question sets are a little confusing. I mentioned the reason for this in the last session, but here it is again. For an accurate CFR, you need ALL the deaths and ALL the cases. If the outbreak is finished in a few weeks or months, the total number of cases (incidence) is the correct denominator. But where the outbreak extends to more than the usual year of reporting, NEITHER annual incidence nor prevalence is valid. So in updated questions (as in the mid-term next week), this will be clear. You should be able to find the TOTAL cases (denominator) and the TOTAL deaths (numerator), regardless of "annual" totals. In short, we have to let the cases have enough time to either die or recover before we can compute the CFR!

* The definitions shows as highlighted all the terms we have discussed, but you should refresh your memory as to the exact meaning of these terms using the dictionary of epidemiology or the definitions in the CCDM.

WEEK	TOPIC	DEFINITIONS	DISEASE in the SPOTLIGHT	READING and extra materials	POWER POINT SETS
#1 JAN 12	INTRO to course INTRO to Epidemiology Basic concepts, purpose, mandate, structure Origins of Epi Hypocrates	**We have discussed the terms that are highlighted . PLEASE BE SURE YOU UNDERSTAND THESE TERMS Asymptomatic Aetiology** Carriers *Communicability* *Contact* Containment *Endemic,* *Enteric* *Enzoötic,* *Epidemic* *Epidemiology* *Epizoötic,* *Etiology* *Fomite* *Frequency* *Host* *Iatrogenic* *Incidence,* Incubation p Index case Isolation *Lesion,* *Latent disease,* *Miasma* *Mortality rates* *- Crude* *- Cause-spec* *- Sex-spec* *- CaseFatality* *- Prop Mort* Nosocomial Outbreak *Pandemic,* *Panzoötic"* *Prevalence* Prodrome Quarantine Reservoir *Sub-clinical* *Surveillance* *Syndrome* *Vector,* *Vehicle,* *Zoönosis*	PLAGUE (as a pandemic disease)	In CCDM please read: chapter on 'PLAGUE' p.463-471	(This content is what we INTEND to cover. Afterwards, the ACTUAL content that was covered will be confirmed. sometimes a lecture runs faster or slower than intended) PP Week 1	Course outline
#2 JAN 19	(Contd...) Graunt Ramazzini Pott, Jenner Lind Semmelweiz Chadwick Snow Koch Introduction to Measurement in epidemiology * Rates & Ratios		CHOLERA (as a pandemic disease)	In CCDM please read: Chapter on 'CHOLERA' p.121-134 We looked at Promed bulletin (31):46 Anthrax - Moldova: livestock Acute rheumatic fever- NZ Syphilis - NZ AI Nigeria H5 (poultry) AI, China H7N9 (human)	PP Week 2 PP Rates PP: Plotting and analyzing the "Epidemic curve"	Please make sure you go through the ppoint set on "rates" and try to calculate the various mortality rates in the THREE TEST QUIZZES included near the end. Also have a look at the "Simpson's Paradox" (the last slide)
#3 JAN 26	Measurements in epidemiology (Contd): * Attack rate tables * Odds Ratio * onset curves *		INFLUENZA (as a pandemic disease)	In CCDM please read Chapter on 'INFLUENZA' p. 315-331	PP: Herd immunity & R₀ PP: Attack-rate tables PP: Odds Ratio
#4 FEB 2
#5 FEB 9
Feb 16	R E A D I N G W E E K
#6 Feb 23	Mid term test scheduled