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YOUCEF DERBAL Ph.D. Electrical and Computer Engineering, Queen's University.
Office: TRS 2-036 Youcef Derbal is an Associate Professor at the Ted Rogers School of Information Technology Management. He received a Doctorate in Electrical and Computer Engineering from Queen's University. Prior to joining Ryerson University in 2003, Dr. Derbal worked in robotics & automation, telecommunications, and software & computing industries. He teaches a variety of topics in information technology, including computer-enabled problem solving, system analysis and design, computer programming, and database design. Dr. Derbal served on the Ryerson University Senate and chaired many school committees, including the Departmental Hiring Committee, the Departmental Evaluation Committee, and the School Curriculum Committee. During the academic years starting from 2009 to 2014, he led the development and deployment of the new Business Technology Management curriculum. He served as the ITM School Director and the School Associate Director during the 2013/2014 and 2019/2021 academic years, respectively. Dr. Derbal research interests span areas in health informatics, mathematical oncology and the applications of artificial intelligence to cancer treatments. Dr. Derbal is a member of the Association for Computing Machinery (ACM), the American Association for the Advancement of Science (AAAS), the Institute of Electrical and Electronics Engineers (IEEE), and the International Society for Computational Biology (ISCB).
Teaching ITM102 Business Information Systems I ITM200 Fundamentals of Programming .NET, Java, Python ITM207 Computer-Enabled Problem Solving ITM305 System Analysis and Design ITM430 System Design & Implementation ITM500 Data and Information Management ITM605 Client Server Applications ITM 901A/B Graduation Project MT8220 Advanced Project Management (Graduate) SM8701 Direct Readings (Graduate) AI in Healthcare AI-Enabled Clinical Decision-Support Systems in Oncology
Research Interests Health Informatics Generative AI Assisted Clinical Decision Support Systems Mathematical Modeling & Simulation of Cancer Adaptive Cancer Therapy
The study of cancer as an adaptive complex system and the development of AI-driven decision-support systems for cancer treatments. The ultimate aim of my research is to apply mathematical modeling, control theory, and artificial intelligence to develop adaptive cancer control strategies towards making cancer a clinically manageable chronic disease.
Selected Publications Derbal Y: Generative Artificial Intelligence as a Catalyst for Effective Cancer Treatments. AI in Clinical Medicine 2025:e5-e5.
Derbal Y.(2025), Generative AI - Assisted Adaptive Cancer Therapy. Cancer Control 2025, 32:10732748251349919. https://doi.org/10.1177/10732748251349919
Derbal Y.(2025), Adaptive Treatment of Metastatic Prostate Cancer Using Generative Artificial Intelligence. Clinical Medicine Insights: Oncology 2025, 19:11795549241311408. https://doi.org/10.1177/10732748251349919
Derbal Y.(2024), Adaptive Cancer Therapy in the Age of Generative Artificial Intelligence. Cancer Control. 2024;31. https://doi.org/10.1177/10732748241264704
Derbal, Y.(2024), Adaptive Control of Tumor Growth. Cancer Control, 2024;31. https://doi.org/10.1177/107327482412308
Derbal, Y.(2023), Cell Adaptive Fitness and Cancer Evolutionary Dynamics. Cancer Informatics, 2023;22. https://doi.org/10.1177/11769351231154679
Derbal, Y.(2022), Can Artificial Intelligence Improve Cancer Treatments? Health Informatics Journal, 2022. https://doi.org/10.1177/14604582221102314 PDF
Derbal, Y.(2021), On Signaling Dysregulation in Cancer, The 2021 International Conference on Computational Science and Computational Intelligence (CSCI21), Las Vegas, December 15-17, 2021. PDF https://doi.org/10.1109/CSCI54926.2021.00126
Derbal, Y. (2020) , Towards machine learning decision support systems for oncology, F1000Research 2020, 9(ISCB Comm J):987 d oi: 10.7490/f1000research.1118248.1
Derbal, Y.(2020), "Modeling Cancer Dynamics," 42nd IEEE Engineering in Medicine and Biology Conference (EMBC), Montreal, July 20-24, 2020, DOI: 10.1109/EMBC44109.2020.9175155 PDF
Derbal, Y.(2020), "Agent-Based Model of Cell Signaling in Cancer," IEEE CCECE Annual Canadian Conference on Electrical and Computer Engineering (CCECE2020), London, August 20-24, 2020, DOI: 10.1109/CCECE47787.2020.9255675
Derbal, Y.(2020), "Towards Machine Learning Decision Support Systems for Oncology," 28th Conference on Intelligent Systems for Molecular Biology (ISMB 2020), Montreal, July 13-16, 2020
Derbal, Y. (2019), "Modeling the Recruitment of Tumor-Infiltrating T Lymphocytes," International Conference on Applied Mathematics, Modeling and Computational Science (AMMCS 2019), Waterloo, August 18-23, 2019. PDF
Derbal, Y.(2018), "The Adaptive Complexity of Cancer," BioMed Research International, vol. 2018, Article ID 5837235, 14 pages, Dec 5 2018. https://doi.org/10.1155/2018/5837235. PDF
Derbal, Y. (2017), "Perspective on the Dynamics of Cancer", BMC Theoretical Biology and Medical Modeling , vol. 14, no. 1, p. 18, Oct 03 2017, https://doi.org/10.1186/s12976-017-0066-5. PDF
Derbal, Y. (2014), "Experimental Profile Modeling of Metabolism", Int. Journal of Computational Bioscience, Vol 4 (1) , 2014.
Derbal, Y. (2014), "State Machine Modeling of MAPK Signaling Pathways", 2014 IEEE Engineering in Medicine and Biology Conference, Chicago, Michigan, 2014. PDF
Derbal, Y.(2013), "Computational Modeling of Estrogen Metabolism", 2013 IASTED Conference on Modeling & Simulation, Banff, Canada, July 2013.
Derbal, Y.(2013), "Exploring Model Integration using Quantized Information Flow " , IEEE - 39th Northeast Annual Bioengineering Conference, Syracuse, New York, April 2013. PDF
Derbal, Y.(2013) "On Modeling of Living Organisms Using Hierarchical Coarse-Grained Abstractions of Knowledge" , J. Biol. Syst. 21, 1350008 (2013) . PDF
Derbal, Y. (2011), "Control Theoretic Modeling of a Genetic Switch" Proceedings of the IEEE 20th Annual Canadian Conference on Electrical and Computer Engineering (CCECE2011), Niagara Falls, Ontario, May, 2011.
Derbal, Y (2009). "Midland: a service oriented cluster computing infrastructure." Springer / Journal of Service Oriented Computing and Applications, Vol. 3 (2), pp. 109-125, June 2009, https://link.springer.com/article/10.1007/s11761-009-0042-y. PDF
Derbal, Y.(2008), "Confidence-based Grid Service Discovery", International Journal of Web and Grid Services, (2008), Issue 2, Vol. 4, pp. 189-210, https://doi.org/10.1504/IJWGS.2008.018887 . PDF
Derbal, Y.(2007) , "A Model of Grid Service Capacity", Journal of Computer Science and Technology, (2007), Issue 4, Vol. 22, pp. 505-514, https://doi.org/10.1007/s11390-007-9074-y . PDF
Derbal, Y. (2007), "Towards a Grid Simulation Platform for Dynamical Systems" Proceedings of The 18th IASTED International Conference on Modeling and Simulation (MS-07), Montreal, Quebec, May 30- June 1, 2007
Derbal, Y. (2007), "Grid Architecture for High Performance Computing" Proceedings of the IEEE 20th Annual Canadian Conference on Electrical and Computer Engineering (CCECE07), Vancouver, British Colombia, April 22-26, 2007
Derbal, Y. (2006), "A New Fault-Tolerance Framework for Grid Computing", Multiagent and Grid Systems- An International Journal, (2006), Issue 2, Vol. 2, pp. 115-133. PDF
Derbal, Y.(2006), "A Probabilistic Scheduling Heuristic for Computational Grids." Multiagent and Grid Systems - An International Journal, (2006), Issue 2, Vol. 1, pp. 45-59. PDF
Derbal, Y.(2006), "Entropic Grid Scheduling." Grid Computing Journal, (2006), Issue 4, Vol. 4, pp. 373-394. PDF
Derbal, Y.(2005), "Decentralized Probabilistic Grid Scheduling: Application to Computational Grids" Proceedings of the 2005 IEEE Conference on Control Applications, Toronto, Canada, ( 2005)
Derbal, Y.(2005), "Service Oriented Grid Resource Modeling and Management" Proceedings of the 1st International Conference on Web Information Systems and Technologies (WEBIST 2005), Miami, Florida, (May 26-28, 2005)
Derbal, Y. (2005), "Probabilistic Resource State Estimation in Networked Environments: The Case of Computational Grids" Third Annual Conference on Communication Networks and Services Research (CNSR2005) Halifax, Nova Scotia, May 16-18, 2005
Derbal, Y. (2005), "A Service Discovery Model for Computational Grids ", IEEE 18th Annual Canadian Conference on Electrical and Computer Engineering (CCECE05), Saskatoon, Saskatchewan, May 1-4, 2005.
Derbal, Y, Bayoumi MM (1993). A neurocontroller for robot manipulators. Proceedings of 1993 IEEE Systems Man and Cybernetics Conference (SMC)
Derbal, Y, Bayoumi MM (1992). A Neural Network-Based Robot Controller. Proceedings of 1992 IEEE Systems Man and Cybernetics Conference (SMC).
Derbal, Y, Bayoumi MM (1992). An Adaptive Neural Network Controller for Robot Manipulator. Proceedings of International Simulation Technology & Workshop on Neural Networks.
Derbal, Y, Bayoumi MM (1992). Neural Networks Control of Robot Manipulators. Proceedings of the 1992 Canadian Conference on Electrical and Computer Engineering.
Derbal, Y, Bayoumi MM (1991). A Neural Network Controller for Robot Manipulators. Proceedings of the 3rd International Conference on Communication and Control.
Derbal, Y, Bayoumi MM (1991). Sliding Mode Control of Robot Manipulator. In ASME Periodical on Modeling Simulation and Control, B, vol. 38 , n0 4, pp 53-64.
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